Electrical stimulation counteracts muscle atrophy associated with aging in humans

European Journal of Translational Myology

Antonio Musarò³  Milan Sedliak²  Manuela De Rossi³  Sandra Zampieri¹  Jan Cvecka²  Stefan Loefler⁵  Helmut Kern⁴  Laura Barberi³  Simone Mosole¹  Samantha Burggraf⁵  Hannah Fruhmann⁵  Ugo Carraro¹ 

[1] Laboratory of Translation Myology, Department of Biomedical Sciences, University of Padova, Italy;Faculty of Sports and Physical Education, Comenius University, Bratislava, Slovakia;DAHFMO-Unit of Histology and Medical Embryology, IIM, La Sapienza University of Rome, Italy;Department of Physical Medicine and Rehabilitation, Wilhelminenspital, Vienna;Ludwig Boltzmann Institute of Electrical Stimulation and Physical Rehabilitation, Vienna, Austria

关键词: electrical stimulation;    FES;    NMES;    senior;    muscle decline;    aging;    atrophy;   

DOI  :  10.4081/ejtm.2013.1780

学科分类：骨科学

来源: Pagepress

【 摘 要 】

Functional and structural muscle decline is a major problem during aging. Our goal was to improve in old subjects quadriceps m. force and mobility functional performances (stair test, chair rise test, timed up and go test) with neuromuscular electrical stimulation (9 weeks, 2-3times/week, 20-30 minutes per session). Furthermore we performed histological and biological molecular analyses of vastus lateralis m. biopsies. Our findings demonstrate that electrical stimulation significantly improved mobility functional performancies and muscle histological characteristics and molecular markers.

【 授权许可】

Unknown