Application of RIFLE criteria in Chinese patients with ANCA-associated renal vasculitis

Clinical and Experimental Rheumatology

Hong Ren¹  Nan Chen¹  Yong-Xi Chen¹  Hao Shi¹  Wen Zhang¹  Xiao-Nong Chen¹  Yao-Wen Xu¹  Ping-Yan Shen¹ 

关键词: Antineutrophil cytoplasmic autoantibody (ANCA);    RIFLE;    CKD;    chronic kidney disease;    RIFLE;    AKI;    acute kidney injury;    vasculitis;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

OBJECTIVES: Antineutrophil cytoplasmic autoantibody (ANCA) associated small vessel vasculitis (AASV) constitutes a group of life-threatening diseases and renal involvement is its most severe and common manifestation. Acute kidney injury (AKI) is common in patients with AASV but the value of RIFLE criteria is still unclear in those patients. METHODS: We performed a retrospective study on patients with AASV in Shanghai Ruijin Hospital from 1997 to 2008. RESULTS: A total of 147 ANCA-associated renal vasculitis patients were studied and 92 developed AKI at diagnosis. According to RIFLE classification, 8 (8/147, 5.44%) patients had AKI-R, 15 (15/147, 10.20%) had AKI-I and 69 (69/147, 46.94%) had AKI-F. Our results demonstrated that more hypertensive patients and higher BVAS were found in patients with AKI-F than those in other groups (p

【 授权许可】

Unknown