Progression of articular and extraarticular damage in oligoarticular juvenile idiopathic arthritis

Clinical and Experimental Rheumatology

claudia Saad Magalhães¹  Jose Eduardo Corrente¹  Juliana de Oliveira Sato¹ 

关键词: Juvenile idiopathic arthritis;    damage;    disability;    oligoarthritis;    outcome.;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

OBJECTIVES: Evaluate damage in oligoarticular JIA, estimating its frequency, risks and probability over time. METHODS: A cross-sectional and retrospective analysis of Juvenile Arthritis Damage Index (JADI) scoring, with both articular and extraarticular components, active joint count, disability index by CHAQ and Steinbrocker class, physician`s global assessment, child`s pain and overall well-being visual analogue scale (VAS), was conducted in patients with oligoarticular JIA. Damage risk factors were estimated by univariate analysis and by generalised linear model. The probability of damage over time was estimated by survival analysis and damage progression rates were calculated by hazard function. RESULTS: Seventy-five JIA cases were assessed, 89.3% persistent and 10.7% extended oligoarthritis, with median follow-up duration 1.7 years (IQR 1.3–3.1). Damage occurred in 38.7%. JADI-A correlated moderately only with the number of limited joints (rs= 0.50, p

【 授权许可】

Unknown