Analysis of disease activity, functional disability and articular damage in patients with juvenile idiopathic arthritis: a prospective outcome study

Clinical and Experimental Rheumatology

Mirjana N. Sefik Bukilica¹  Dragoslav B. Jablanovic¹  Nemanja S. Damjanov¹  Roksanda M. Stojanovic¹  Gordana Z. Susic¹  Ivan I. Soldatovic¹  Nada N. Pejnovic¹ 

关键词: Juvenile idiopathic arthritis;    outcome;    functional disability;    articular damage;    Functional disability;    juvenile idiopathic arthritis;    Articular damage;    juvenile idiopathic arthritis;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

OBJECTIVES: We longitudinally studied outcomes of patients with juvenile idiopathic arthritis (JIA) using the Childhood Health Assessment Questionnaire (CHAQ) for physical disability and the Juvenile Arthritis Damage Index for articular (JADI-A) and extra-articular damage (JADI-E), and we correlated them with various disease activity variables. METHODS: Eighty-seven patients with JIA were included in the prospective follow-up study with median age 14 years (4.6–18.0), disease duration 5.2 years (2.0–18.9) and follow-up of 4.0 years (2.0–5.2). Besides JADI-A and JADI-E, and the assessment of active joints count, joints with limited mobility, ESR, CHAQ and radiographic damage of joints was also done. A correlation analysis of CHAQ and JADI with various disease activity variables was performed. RESULTS: The patient`s distribution of JIA subtypes were polyarticular (32), systemic onset (13), oligoarticular (31), and enthesitis related arthritis (11). After a follow-up period, 46% patients had active disease compared to 83% patients at baseline (p

【 授权许可】

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