Side effects and management of side effects of methotrexate in rheumatoid arthritis

Clinical and Experimental Rheumatology

Katinka Albrecht¹  Ulf Mueller-Ladner¹ 

关键词: Rheumatoid arthritis;    methotrexate;    side effects;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

Low-dose methotrexate (MTX) remains the first-line treatment option among the disease-modifying antirheumatic drugs in patients with rheumatoid arthritis. However, diverse side effects are the major reason for MTX withdrawal and change of treatment. The following article reviews the published data on general and organ-specific side effects and outlines the current recommendations addressing prevention and management of MTX-associated adverse effects.

【 授权许可】

Unknown