Clinical and Experimental Rheumatology | |
A case of Brucella spondylitis in a patient with psoriatic arthritis receiving infliximab. | |
I. Vrabie1  A.K. Zikou11  P.V. Voulgari1  A.A. Drosos1  M.I. Argyropoulou1  C.E. Papagoras1  | |
关键词: Brucella spondylitis; anti-TNFα agents; infliximab; psoriatic arthritis.; | |
DOI : | |
学科分类:医学(综合) | |
来源: Pacini Editore SpA | |
【 摘 要 】
ABSTRACT:A 69-year-old woman with psoriatic arthritis treated with infliximab presented with low back pain of recent onset and fever. Serological, microbiological and imaging studies revealed Brucella spondylitis at the L5-S1 level. Immunosuppressive therapy was suspended and antibiotic therapy including doxycycline and rifampicin was administered for six months. The patient responded adequately with clinical and laboratory improvement and a considerable remission of spondylitis on repeat magnetic resonance imaging scan. The pathophysiology of tumor necrosis factor (TNF) α in Brucellosis and the role of anti-TNFα therapy are discussed.
【 授权许可】
Unknown
【 预 览 】
Files | Size | Format | View |
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RO201912020416594ZK.pdf | 976KB | download |