Axonal neuropathy with prolonged sulphasalazine use

Clinical and Experimental Rheumatology

A.E. Voskuyl¹  B.W. Van Oosten¹  M. Liedorp¹ 

关键词: Neuropathy;    sulphasalazine;    arthritis;    adverse drug reaction.;   

DOI  :  

学科分类：医学（综合）

来源: Pacini Editore SpA

【 摘 要 】

Sulphasalazine, one of the 5-amino-salicylates, is widely used for the treatment of inflammatory bowel diseases and arthritis. Among the reported adverse effects are blood dyscrasias and hepatic failure. Peripheral neuropathy has been reported as a rare adverse drug reaction to sulphasalazine. Most reported patients developed symptoms several weeks after onset of treatment. We describe a patient with an axonal polyneuropathy that occurred after two years of treatment with sulphasalazine.

【 授权许可】

Unknown