The diversity of globin‐coupled sensors

FEBS Letters

Hou, Shaobin¹  Freitas, Tracey Allen K¹  Alam, Maqsudul¹ 

[1] Department of Microbiology, Snyder Hall 207, 2538 The Mall, University of Hawaii, Honolulu, HI 96822, USA

关键词: Globin;    Archaeon;    Heme-based sensor;    Globin-coupled sensor;   

DOI  :  10.1016/S0014-5793(03)00923-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The recently discovered globin-coupled sensors (GCSs) are heme-containing two-domain transducers distinct from the PAS domain superfamily. We have identified an additional 22 GCSs with varying multi-domain C-terminal transmitters through a search of the complete and incomplete microbial genome datasets. The GCS superfamily is composed of two major subfamilies: the aerotactic and gene regulators. We postulate the existence of protoglobin in Archaea as the predecessor to the chimeric GCS.

【 授权许可】

Unknown