Omnipotent RNA

FEBS Letters

Spirin, Alexander S¹ 

[1] Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia

关键词: Non-coding RNA;    RNA folding;    RNA recombination;    RNA world;    RNA colony;    Universal precursor;   

DOI  :  10.1016/S0014-5793(02)03434-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The capability of polyribonucleotide chains to form unique, compactly folded structures is considered the basis for diverse non-genetic functions of RNA, including the function of recognition of various ligands and the catalytic function. Together with well-known genetic functions of RNA – coding and complementary replication – this has led to the concept of the functional omnipotence of RNA and the hypothesis that an ancient RNA world supposedly preceded the contemporary DNA–RNA–protein life. It is proposed that the Woese universal precursor in the ancient RNA world could be a cell-free community of mixed RNA colonies growing and multiplying on solid surfaces.

【 授权许可】

Unknown