NADP‐malic enzyme from plants: a ubiquitous enzyme involved in different metabolic pathways

FEBS Letters

Drincovich, Marı́a F.¹  Andreo, Carlos S.¹  Casati, Paula¹ 

[1] Centro de Estudios Fotosintéticos y Bioquı́micos, Universidad Nacional de Rosario, CONICET, Suipacha 531, 2000 Rosario, Argentina

关键词: NADP-malic enzyme;    C4 plant;    CAM plant;    C3 plant;    Molecular evolution;   

DOI  :  10.1016/S0014-5793(00)02331-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

NADP-malic enzyme (NADP-ME) is a widely distributed enzyme that catalyzes the oxidative decarboxylation of L-malate. Photosynthetic NADP-MEs are found in C₄ bundle sheath chloroplasts and in the cytosol of CAM plants, while non-photosynthetic NADP-MEs are either plastidic or cytosolic in various plants. We propose a classification of plant NADP-MEs based on their physiological function and localization and we describe recent advances in the characterization of each isoform. Based on the alignment of amino acid sequences of plant NADP-MEs, we identify putative binding sites for the substrates and analyze the phylogenetic origin of each isoform, revealing several features of the molecular evolution of this ubiquitous enzyme.

【 授权许可】

Unknown