Genomic Exploration of the Hemiascomycetous Yeasts: 16. Candida tropicalis

FEBS Letters

Dujon, Bernard¹  Artiguenave, François²  Blandin, Gaëlle¹  Wincker, Patrick²  Ozier-Kalogeropoulos, Odile¹ 

[1] Unité de Génétique Moléculaire des Levures (URA 2171 CNRS, UFR 927 Univ. P. and M. Curie), Département des Biotechnologies, Institut Pasteur, 25 rue du Dr Roux, F-75724 Paris Cedex 15, France;Genoscope, 2 rue Gaston Crémieux, F-91000 Evry, France

关键词: Genetic code;    Diploid species;    Intron;    rDNA;   

DOI  :  10.1016/S0014-5793(00)02287-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The genome of the diploid hemiascomycetous yeast Candida tropicalis, an opportunistic human pathogen and an important organism for industrial applications, was explored by the analysis of 2541 Random Sequenced Tags (RSTs) covering about 20% of its genome. Comparison of these sequences with Saccharomyces cerevisiae and other species permitted the identification and the analysis of a total of more than 1000 novel genetic elements of C. tropicalis. Moreover, the present study confirms that in C. tropicalis, the rare CUG codon is read as a serine and not a leucine. The sequences have been deposited at EMBL with the accession numbers AL438875–AL441602.

【 授权许可】

Unknown