Genomic Exploration of the Hemiascomycetous Yeasts: 5. Saccharomyces bayanus var. uvarum

FEBS Letters

Casaregola, Serge³  Aigle, Michel¹  Bon, Elisabeth¹  Artiguenave, François²  Durrens, Pascal¹  Neuvéglise, Cécile³  Wincker, Patrick² 

[1] Laboratoire de Biologie Cellulaire de la Levure, UMR 5095, 1 rue Camille Saint-Saëns, F-33077 Bordeaux Cedex, France;Génoscope, Centre National de Séquençage, 2 rue Gaston Crémieux, P.O. Box 191, F-91057 Evry Cedex, France;Collection des Levures d'Intérêt Biotechnologique, Laboratoire de Génétique Moléculaire et Cellulaire, INRA UMR 216, CNRS URA 1925, INA-PG, P.O. Box 01, F-78850 Thiverval-Grignon, France

关键词: Centromere;    Ty;    Translocation;    Saccharomyces bayanus;   

DOI  :  10.1016/S0014-5793(00)02276-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Saccharomyces bayanus var. uvarum investigated here is the species closest to Saccharomyces cerevisiae. Random sequence tags (RSTs) allowed us to identify homologues to 2789 open reading frames (ORFs) in S. cerevisiae, ORFs duplicated in S. uvarum but not in S. cerevisiae, centromeres, tRNAs, homologues of Ty1/2 and Ty4 retrotransposons, and a complete rDNA repeat. Only 13 RSTs seem to be homologous to sequences in other organisms but not in S. cerevisiae. As the synteny between the two species is very high, cases in which synteny is lost suggest special mechanisms of genome evolution. The corresponding RSTs revealed that S. uvarum can exist without any S. cerevisiae DNA introgression. Accession numbers are from AL397139 to AL402278 in the EMBL databank.

【 授权许可】

Unknown