Complementary packing of α‐helices in proteins

FEBS Letters

Efimov, Alexander V¹ 

[1] Institute of Protein Research, Russian Academy of Sciences, 142292 Pushchino, Moscow Region, Russia

关键词: Complementarity;    Helix packing;    Hydrophobic stripe;    Packing angle;    Protein structure;   

DOI  :  10.1016/S0014-5793(99)01507-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The packing of α-helices in proteins is restricted by both the principle of close packing and the chemical nature of side chains. As a result, (1) α-helical surfaces forming the interface should be complementary to each other, (2) hydrophobic stripes of the α-helices should fit together like pieces of a jigsaw puzzle, and (3) buried polar side chains (if there are any) should be arranged in a complementary fashion.

【 授权许可】

Unknown