Phospholipin, a novel heterodimeric phospholipase A2 from Pandinus imperator scorpion venom

FEBS Letters

Possani, Lourival D¹  Conde, Renaud¹  Zamudio, Fernando Z¹  Becerril, Baltazar¹ 

[1] Department of Molecular Recognition and Structural Biology, Biotechnology Institute, National Autonomous University of Mexico, Avenida Universidad, 2001, Apartado Postal 510-3, Cuernavaca 62210, Mexico

关键词: Phospholipase A2;    Amino acid sequence;    Nucleotide sequence;    Scorpion venom;    Pandinus imperator;   

DOI  :  10.1016/S0014-5793(99)01392-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The primary structure of a phospholipase A2, with unique structural and functional characteristics, was determined. The large subunit has 108 amino acid residues, linked by a disulfide bridge to the small subunit, which contains 17 residues. Its gene was cloned from a cDNA library. The nucleotide sequence showed that the same RNA messenger encodes both subunits, separated only by a pentapeptide, that is processed during maturation.

【 授权许可】

Unknown