Conserved sequence motifs in levansucrases and bifunctional β‐xylosidases and α‐l‐arabinases

FEBS Letters

Naumoff, Daniil G¹ 

[1] State Institute for Genetics and Selection of Industrial Microorganisms, I-Dorozhny proezd, 1, Moscow 113545, Russia

关键词: Glycosyl hydrolase;    β-Fructosidase superfamily;    Levansucrase;    β-Xylosidase;    Multiple sequence alignment;   

DOI  :  10.1016/S0014-5793(99)00369-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Comparison of the amino acid sequences of two families of glycosyl hydrolases reveals that they are related in a region in the central part of the sequences. One of these families (GH family 68) includes levansucrases and the other one (glycosyl hydrolase family 43) includes bifunctional β-xylosidases and α-l-arabinofuranosidases. The similarity of the primary structure of proteins from these families allows us to consider the invariant glutamate residue as a component of their active center. It is shown for the first time that glycosyl hydrolases recognizing different glycofuranoside residues can have a common sequence motif.

【 授权许可】

Unknown