Computational analyses and annotations of the Arabidopsis peroxidase gene family

FEBS Letters

Østergaard, Lars¹  Brunak, Søren²  Pedersen, Anders G²  Jespersen, Hans M¹  Welinder, Karen G¹ 

[1] Department of Protein Chemistry, Institute of Molecular Biology, University of Copenhagen, Øster Farimagsgade 2A, DK-1353 Copenhagen K, Denmark;Center for Biological Sequence Analysis, The Technical University of Denmark, Building 208, DK-2800 Lyngby, Denmark

关键词: Adenine-rich 5′ untranslated region;    Neural network prediction;    Peroxidase;    Plant cDNA;    Translational control;   

DOI  :  10.1016/S0014-5793(98)00849-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Classical heme-containing plant peroxidases have been ascribed a wide variety of functional roles related to development, defense, lignification, and hormonal signaling. More than 40 peroxidase genes are now known in Arabidopsis thaliana for which functional association is complicated by a general lack of peroxidase substrate specificity. Computational analysis was performed on 30 near full-length Arabidopsis peroxidase cDNAs for annotation of start codons and signal peptide cleavage sites. A compositional analysis revealed that 23 of the 30 peroxidase cDNAs have 5′ untranslated regions containing 40–71% adenine, a rare feature observed also in cDNAs which predominantly encode stress-induced proteins, and which may indicate translational regulation.

【 授权许可】

Unknown