S‐Carbocysteine‐lysine salt monohydrate and cAMP cause non‐additive activation of the cystic fibrosis transmembrane regulator channel in human respiratory epithelium

FEBS Letters

Meyer, Giuliano¹  Daffonchio, Luisa²  Doppierio, Sonia¹  Cremaschi, Dario¹ 

[1] Dipartimento di Fisiologia e Biochimica Generali, Sezione di Fisiologia Generale, Università degli Studi di Milano, via Celoria 26, 20133 Milano, Italy;Dompè Spa, via S. Martino 12, 20122 Milano, Italy

关键词: S-Carbocysteine-lysine salt monohydrate;    Cl− channel;    Respiratory epithelium;    8-Br-cAMP;    8-bromoadenosine 3′:5′-cyclic monophosphate;    CF;    cystic fibrosis;    CFTR;    cystic fibrosis transmembrane regulator;    db-cAMP;    dibutyryl adenosine 3′:5′-cyclic monophosphate;    DIDS;    4;    4′-diisothiocyanostilbene-2;    2′-disulphonic acid;    DPC;    diphenylaminecarboxylic acid;    NMG;    N-methylglucamine;    NMGCl;    N-methylglucamine-Cl;    ORCC;    outwardly rectifying Cl− channel;    PGE1;    prostaglandin E1;    S-CMC-Lys;    S-carbocysteine-lysine salt monohydrate;    SITS;    4-acetamido-4′-isothiocyanostilbene-2;    2′-disulphonic acid.;   

DOI  :  10.1016/S0014-5793(97)00074-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

© 1997 Federation of European Biochemical Societies.

【 授权许可】

Unknown