Transforming growth factor‐β1 induces activation of Ras, Raf‐1, MEK and MAPK in rat hepatic stellate cells

FEBS Letters

Scheibe, Roland²  Hempel, Ute²  Krautwald, Stefan¹  Wenzel, Klaus-Wolfgang²  Reimann, Thomas²  Seidel, Dagmar²  Axmann, Andreas² 

[1]Fraunhofer Institute for Toxicology and Aerosol Research, Nikolai-Fuchs-Straße 1, D-30625 Hannover, Germany

[2]Institute of Physiological Chemistry, Medical Faculty Carl Gustav Carus, Technical University Dresden, Karl-Marx-Straße 3, D-01109 Dresden, Germany

关键词: Transforming growth factor-β1;    Ras;    Raf-1;    MEK;    MAPK;    Hepatic stellate cell;    Signal transduction;    bFGF;    basic fibroblast growth factor;    EGF;    epidermal growth factor;    EGTA;    ethyleneglycol-bis (β-amino-ethyl)-N;    N;    N′;    N′-tetraacetic acid;    MBP;    myelin basic protein;    MAPK;    mitogen-activated protein kinase;    MEK;    MAPK or ERK kinase;    PDGF;    platelet derived growth factor;    PMSF;    phenylmethylsulfonylfluoride;    TGF-β1;    transforming growth factor-β1;   

DOI  :  10.1016/S0014-5793(97)00024-0

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

© 1997 Federation of European Biochemical Societies.

【 授权许可】

Unknown