FEBS Letters | |
A novel gene family encoding proteins with highly differing structure because of a rapidly evolving exon | |
Lundwall, Åke1  Lazure, Claude1  | |
[1]Department of Clinical Chemistry, Lund University, Malmö University Hospital, S-214 01 Malmö, Sweden | |
关键词: Semen; Protein; Rapid; Exon; Gene; Evolution; | |
DOI : 10.1016/0014-5793(95)01076-Q | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
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【 摘 要 】
Despite vast differences in primary structure, it is here shown that several predominant semen proteins are encoded by genes that belongs to a common family. Members have their transcription unit split into three exons: the first encoding the signal peptide, the second the secreted protein, while the third exon solely consists of 3′ non-translated nucleotides. The first and and the third exon are conserved between members, but the second exon is not. The genes for human semenogelins I and II, rat SVSII, SVSIV, SVSV and guinea pig GP1 and GP2 belong to this gene family.
【 授权许可】
Unknown
【 预 览 】
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RO201912020301774ZK.pdf | 441KB | ![]() |