FEBS Letters | |
Antioxidant system in rat testicular cells | |
Jégou, Bernard1  Fouchard, Marie-Hélène1  Bauché, Françoise1  | |
[1] GERM, INSERM CJF 91-04, Université de Rennes I, Campus de Beaulieu, 35042 Rennes Cedex, Bretagne, France | |
关键词: Testicular cell; Glutathione; Antioxidant enzyme; Reactive oxygen; Rat; | |
DOI : 10.1016/0014-5793(94)00709-8 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
The activity of the enzymes involved in the antioxidant defence — superoxide dismutase (SOD), glutathione peroxidase (GPx), reductase (GR) S-transferase (GST) — as well as the glutathione (GSH) levels were measured in different rat testicular cell populations. A differential distribution of these components among testicular cell types was clearly observed. Sertoli and peritubular cells had elevated SOD and GSH-dependent enzyme activities associated with a high GSH content. Compared with the somatic cells, pachytene spermatocytes (PS) round spermatids (RS) presented a different antioxidant system characterized by higher SOD activity and GSH content associated with very low GSH-dependent enzyme activity. Spermatozoa exhibited the same enzymatic system as PS and RS but were devoid of GSH. Interstitial tissue displayed high GSH content, moderate SOD and GSH-related enzyme activity except for GPx which was very elevated. It is concluded that the different categories of testicular cells probably display a highly variable susceptibility to oxidative stress.
【 授权许可】
Unknown
【 预 览 】
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RO201912020299867ZK.pdf | 654KB | download |