Anion‐mediated lysine—arginine interaction evidence in Chaetopterus variopedatus sperm protamine

FEBS Letters

Tomei, Licia²  Petrocellis, Luciano De¹  Piscopo, Marina²  Geraci, Giuseppe² 

[1] Institute of Cybernetics, CNR, Via Toiano 6, 80072, Arco Felice, Italy;Department of Genetics, General and Molecular Biology, University of Naples ‘Federico II’, Via Mezzocannone 8, 80134 Naples, Italy

关键词: Ionic interaction;    Protein structure;    Protamine;    Chaetopterus variopedatus;   

DOI  :  10.1016/0014-5793(93)81696-W

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Chaetopterus ariopedatus sperm protamine is a stable oligomer. Specific amino acid side chain modifications show that the oligomeric structure depends on anion-mediated lysine—arginine interactions. The occurrence of this type of interaction is confirmed by the finding that Poly-l-arginine readily forms aggregates with Poly-l-lysine or with the native but not with the protamine with carbamylated ε-amino groups.

【 授权许可】

Unknown