The sarco(endo)plasmic reticulum Ca2+‐ATPase mRNA isoform, SERCA 3, is expressed in endothelial and epithelial cells in various organs

FEBS Letters

Wuytack, Frank¹  Marotte, Françoise³  Samuel, Jane-Lyse³  Anger, Marielle²  Lompré, Anne-Marie²  Rappaport, Lydie³ 

[1] Laboratorium voor Fysiologie, Universiteit Leuven, Campus Gasthuisberg, B-3000 Leuven, Belgium;INSERM U 275 - LOA - ENSTA, Ecole Polytechnique, Centre de l'Yvette, 91120 Palaiseau, France;INSERM U 127, Hôpital Lariboisière, 41 Bd de la Chapelle, 75010 Paris, France

关键词: Sarcoplasmic reticulum;    Ca2+-ATPase mRNA isoform;    In situ hybridization;    Endothelial cell;    Epithelial cell;   

DOI  :  10.1016/0014-5793(93)81677-R

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The sarco(endo)plasmic reticulum Ca²⁺-ATPase mRNA isoform, SERCA 3, was previously shown to be expressed in a great variety of muscle and non-muscle tissues [(1989) J. Biol. Chem. 264, 18561–18568] but its cellular localization within these organs was unknown. We have used in situ hybridization and RNase protection techniques to demonstrate that SERCA 3 mRNA is expressed in specific cell types, namely the endothelial and epithelial cells.

【 授权许可】

Unknown