A gene homologous to the reg gene is expressed in the human pancreas

FEBS Letters

Gharib, Bouchra¹  Giorgi, Dominique¹  Bergé-Lefranc, Jean-Louis¹  Bartoli, Catherine¹  Dagorn, Jean-Charles¹  Sansonetti, Alice¹ 

[1] Unité 315 de l'INSERM, 46, Boulevard de la Gaye, 13258 Marseille Cedex 9, France

关键词: Pancreas;    Lithostathine;    reg gene;   

DOI  :  10.1016/0014-5793(93)81006-L

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have determined the nucleotide sequence of reg1 a human genomic DNA fragment homologous to the reg gene which is expressed in the exocrine pancreas and regenerating islets. Sequence comparisons of reg and reg1 suggested similar exonintron organisation. Based on this assumption, specific oligonucleotides for reg1 exons were used to demonstrate expression of the reg1 gene in pancreas and liver. The proteins encoded by reg and reg1 comprise 166 amino acids and differ by 22 amino acids only.

【 授权许可】

Unknown