Electrical stimulation partly reverses the muscle insulin resistance caused by tenotomy

FEBS Letters

Budohoski, L.¹  Langfort, J.¹  Nazar, K.¹  Czarnowski, D.²  Kaciuba-Uściłko, H.¹  Górski, J.² 

[1] Department of Applied Physiology, Medical Research Centre, Polish Academy of Sciences, Jazgarzewska 17, 00-730 Warsaw, Poland;Department of Physiology, Medical School, Mickiewicza 2, 15-230 Białystok, Poland

关键词: Muscle inactivity;    Electrical stimulation;    Insulin sensitivity;    Glucose transport;    Lactate production;    Glycogen synthesis;   

DOI  :  10.1016/0014-5793(93)81159-W

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

It was shown that 15-min electrical stimulation of the rat sciatic nerve greatly increases the in vitro measured sensitivity of lactate formation, glucose transport, and glycogen synthesis to insulin, impaired by previous tenotomy. The insulin sensitivity of all these processes was, however, still below that found in the stimulated intact soleus muscle. Extending the stimulation up to 30 min did not cause any further changes in insulin sensitivity either in tenotomized or in intact muscles.

【 授权许可】

Unknown