Does biocatalysis involve inhomogeneous kinetics?

FEBS Letters

Demchenko, Alexander P.¹ 

[1] Department of Biophysics, A.V. Palladin Institute of Biochemistry, Kiev, 252030, Ukraine U.S.S.R.

关键词: Biocatalytic mechanism;    Inhomogeneous kinetics;    Transition state theory;    Protein dynamics;    TST;    transition state theory;    LE;    locally excited;    CT;    charge transfer;   

DOI  :  10.1016/0014-5793(92)81334-I

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Biocatalytic reactions can occur according to two very different mechanisms: homogeneous, which is described by standard transition state theory (TST) and its modifications, and inhomogeneous (polychromatic), which is characteristic for some of the charge-transfer reactions in liquids and amorphous solids. While most data published on enzyme reactions are interpreted on the basis of homogeneous kinetics, the important recent findings suggest the involvement of inhomogeneous kinetics mechanism.

【 授权许可】

Unknown