A marine algal Na+‐activated ATPase possesses an immunologically identical epitope to Na+,K+‐ATPase

FEBS Letters

Fujii, Tadashi²  Ikawa, Yoji¹  Satoh, Shinobu²  Hara, Yukichi¹  Wada, Masato²  Urayama, Osamu¹ 

[1] Department of Biochemistry, Tokyo Medical and Dental University School of Medicine, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113, Japan;Institute of Biological Sciences, The University of Tsukuba City, Ibaraki 305, Japan

关键词: Akashiwo Na+-ATPase;    Na+.K+-ATPase;    Epitope mapping;    Antibody;   

DOI  :  10.1016/0014-5793(92)80787-H

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Immunological homology was investigated between Heterosigma akashiwo (a marine alga) Na⁺-activated ATPase and animal Na⁺,K⁺-ATPase. The former polypeptide [(1989) Plant Cell Physiol. 30, 923-928] reacted with anti-serum raised against the amino-terminal half of the pig kidney Na⁺,K⁺-ATPase α subunit. It is suggested that the Na⁺,K⁺-ATPase epitope within the amino-terminal region is conserved in the plant Na⁺-activated ATPase, and the region containing the epitope may be important for Na ion transport.

【 授权许可】

Unknown