De‐novo biosynthesis of chlorinated aromatics by the white‐rot fungus Bjerkandera sp. BOS55 Formation of 3‐chloro‐anisaldehyde from glucose

FEBS Letters

Field, Jim A.²  de Bont, Jan A.M.²  Wijnberg, Joannes B.P.A.¹  de Jong, Ed²  Dings, Jacobus A.F.M.² 

[1] Department of Organic Chemistry, Agricultural University Wageningen, Wageningen, The Netherlands;Division of Industrial Microbiology, Department of Food Science, Agricultural University Wageningen, Wageningen, The Netherlands

关键词: Veratryl alcohol;    Lignin degradation;    Bjerkandera;    Phanerochaete chrysosporium;    Anisaldehyde;    3-Chloro-anisaldehyde;   

DOI  :  10.1016/0014-5793(92)80672-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The white-rot fungus Bjerkandera sp. BOS55 produced de-novo several aromatic metabolites. Besides veratryl alcohol and veratraldehyde, compounds which are known to be involved in the ligninolytic system of several other white-rot fungi, other metabolites were formed. These included anisaldehyde, 3-chloro-anisaldehyde and a yet unknown compound containing two chlorine atoms. Additionally GC/MS analysis revealed the production of small amounts of anisyl alcohol and 3-chloro-anisyl alcohol. After 14 days, the extracellular fluid of Bjerkandera BOS55 contained 100 μM veratraldehyde and 50 μM 3-chloro-anisaldehyde. This is the first report of de-novo biosynthesis of simple chlorinated aromatic compounds by a white-rot fungus. Anisaldehyde and 3-chloro-anisaldehyde were also produced by Bjerkandera adusta but not by Phanerochaete chrysosporium.

【 授权许可】

Unknown