Relative‐residue surface‐accessibility patterns reveal myoglobin and catalase similarity

FEBS Letters

Osguthorpe, D.J.¹  Cockcroft, V.B.¹ 

[1] Molecular Graphics Unit, Bath University, Bath BA2 7AY, UK

关键词: Relative-residue surface-accessibility pattern;    Non-homologous similarity;    Myoglobin;    Catalase;   

DOI  :  10.1016/0014-5793(91)81173-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A novel sliding-window search method using relative-residue surface-accessibility patterns identified extensive, but unsuspected, structural similarity over a 3-helix region in the C-terminus of the evolutionarily unrelated proteins sperm-whale myoglobin and beef liver catalase. This clear example of structural similarity between non-homologous proteins highlights the importance of relative-residue surface-accessibility patterns in understanding the local folded structure in proteins.

【 授权许可】

Unknown