Molecular structure of the Japanese hepatitis C viral genome

FEBS Letters

Nakagawa, Mosanori¹  Shimotohno, Kunitada¹  Ootsuyama, Yuko¹  Hijikata, Makoto¹  Ohkoshi, Showgo¹  Kato, Nobuyuki¹  Muraiso, Kanae¹ 

[1] Virology Division, National Cancer Center Research Institute, 5-1-1 Tsukiji, Chuo-ku, Tokyo 104, Japan

关键词: Non-A;    non-B hepatitis;    RNA virus;    HCV-J;    Amino acid sequence;   

DOI  :  10.1016/0014-5793(91)80322-T

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The amino acid sequence of the polyprotein deduced from the nucleotide sequence of the Japanese hepatitis C virus genome (N. Kato et. al. (1990) Proc. Natl. Acad. Sci. USA 87, 9524–9528)indicated that this virus is a member of a new class of positive-stranded RNA viruses. Several domains of this polyprotein also showed weak homology with those of flaviviruses and pestiviruses including the chymotrypsin-like serine proteinase. NTPase and RNA-dependent RNA polymerase

【 授权许可】

Unknown