2D crystal forms of annexin IV on lipid monolayers

FEBS Letters

Leonard, K.¹  Crumpton, M.J.²  Newman, R.H.² 

[1] European Molecular Biology Laboratory, Postfach 10 2209, D-6900 Heidelberg 1, Germany;Imperial Cancer Research Fund Laboratories, PO Box 123, Lincoln's Inn Fields, London WC2A 3PX, UK

关键词: Annexin;    Two-dimensional crystal;    Lipid monolayer;   

DOI  :  10.1016/0014-5793(91)80240-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Two-dimensional crystalline arrays of annexin IV were generated by interaction of the purified protein with a phospholipid monolayer. Image analysis of electron micrographs of the protein crystals, which diffracted to 3.5 nm respectively, revealed p6 and p3 symmetry. Annexin IV gave two crystal forms with unit cells of 18 × 18 nm and 28 × 28 nm. The former unit cells wax similar to a previously described form of annexin VI. The implications of those observations are discussed.

【 授权许可】

Unknown