Evidence for aggregation of endothelin 1 in water

FEBS Letters

Demaille, Jacques²  Heitz, Frédéric¹  Bennes, René¹  Chabrier, Pierre-Etienne³  Calas, Bernard² 

[1] UA 330 CNRS, B.P. 5051, F-34033 Montpellier Cedex, France;LP 8402 CNRS and U249 INSERM, B.P. 5051, F-34033 Montpellier Cedex, France;I.H.B. 72, Avenue des Tropiques, F-91940 Les Ulis, France

关键词: Endothelin;    Aggregation;    Circular dichroism;    Surface tension;    Conductivity;   

DOI  :  10.1016/0014-5793(90)80497-7

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

In this report it is shown by CD spectroscopy that endothelin 1, when dissolved in water, is able to present intermolecular interactions leading to formation of aggregates. Surface tension and conductivity measurements suggest that the aggregation occurs through formation of micelles with a CMC of about 2.2 × 10⁻⁵ M.

【 授权许可】

Unknown