Membrane elasticity of mouse dorsal root ganglion neurons decreases with aging

FEBS Letters

Horie, Hidenori²  Ikuta, Shinichiro¹  Takenaka, Toshifumi² 

[1] Department of Physics, Waseda University, Shiujuku-ku TokyoJapan;Department of Physiology, School of Medicine, Yokohama City University, 3-9 Fukuura, Kanazawaku, YokohamaJapan

关键词: Membrane elasticity;    Aging;    Tissue culture;    Dorsal root ganglion neuron;   

DOI  :  10.1016/0014-5793(90)81109-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Elastic area compressibility modulus (EACM) method was applied to measure the membrane elasticity of cultured dorsal root ganglion neurons from fetal and 3-month-old mice. The values of the EACM were 21.3 in 3-month-old neurons and 2.8 in fetal neurons. These results indicate that neural cell membrane elasticity decreases with aging.

【 授权许可】

Unknown