Regulation of plant gene expression by antisense RNA

FEBS Letters

van Blokland, R.¹  van Tunen, A.J.¹  Mol, J.N.M.¹  de Lange, P.¹  Stuitje, A.R.¹  van der Krol, A.R.¹ 

[1] Department of Genetics, Vrije Universiteit, De Boelelaan 1087, 1081 HV Amsterdam, The Netherlands

关键词: Antisense RNA;    Sense RNA;    Co-suppression;    Gene interaction;    Gene silencing;   

DOI  :  10.1016/0014-5793(90)81298-3

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Regulation of gene expression by antisense RNA was first discovered as a naturally-occurring phenomenon in bacteria. Recently natural antisense RNAs have been found in a variety of eukaryotic organisms; their in vivo function is, however, obscure. Deliberate expression of antisense RNA in animal and plant systems has lead to successful down-regulation of specific genes. We will review the current status of antisense gene action in plant systems. The recent discovery that ‘sense’ genes are able to mimic the action of antisense genes indicates that (anti)sense genes must operate by mechanisms other than RNA-RNA interaction.

【 授权许可】

Unknown