Eukaryotic DNA helicases

FEBS Letters

Thömmes, Pia¹  Hübscher, Ulrich¹ 

[1]Department of Pharmacology and Biochemistry, University Zürich Irchel, Winterthurerstrasse 190, CH-8057 Zürich, Switzerland

关键词: DNA replication;    DNA helicase;    Eukaryotic;    ATPase;    Nucleoside triphosphate hydrolysis;   

DOI  :  10.1016/0014-5793(90)81279-W

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

DNA is very stable in its double-stranded form. For many processes of DNA metabolism, such as replication, repair, recombination and transcription, the DNA has to be brought transiently into a single-stranded form. DNA helicases are enzymes capable of melting the hydrogen bonds of base pairs by using the energy of nucleoside-5'-triphosphate hydrolysis. This minireview focusses on the current knowledge of DNA helicases from eukaryotic cells.

【 授权许可】

Unknown