The complete amino acid sequence of bullfrog (Rana catesbeiana) parvalbumin pI4.97

FEBS Letters

Tanokura, Masaru²  Sasaki, Takuji¹  Asaoka, Kazuo³ 

[1] Department of Food Science and Technology, School of Agriculture, Nagoya University, Chikusa, Aichi 464-01, Japan;Department of Physiology, Medical College of Oita, Hasama, Oita 879-56, Japan;Department of Biochemistry, Primate Research Institute, Kyoto University, Inuyama, Aichi 484, Japan

关键词: Parvalbumin;    Calcium binding protein;    Muscle protein;    Amino acid sequence;    Molecular evolution;    Frog phylogeny;    PA;    parvalbumin: PA x;    parvalbumin pIx;   

DOI  :  10.1016/0014-5793(90)81020-O

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The primary structure of the parvalbumin (pI4.97) from bullfrog, Rana catesbeiana, skeletal muscle has been determined. It is composed of 110 amino acid residues and a free amino terminus, and has a molecular mass of 11919. The amino add sequences which are thought to be functionally important sites are also conserved in the bullfrog parvalbumin. The calculated phylogenic tree indicates that this parvalbumin belongs to the α group of parvalbumins. The mutation rate of parvalbumin was fairly rapid in frogs compared to mammals. The subdivergence of frogs is also discussed.

【 授权许可】

Unknown