Does a 2 ← 5β‐turn structure exist in enkephalins?

FEBS Letters

Moret, E.¹  Hunston, R.N.¹  Lauterwein, J.¹  Gerothanassis, I.P.¹ 

[1] Institut de Chimie Organique, Université de Lausanne, rue de la Barre 2, CH-1005 Lausanne, Switzerland

关键词: 17O-NMR;    Enkephalin;    β-Turn structure;   

DOI  :  10.1016/0014-5793(90)80182-I

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The ¹⁷O chemical shifts of the Gly-2 and Gly-3 oxygens of a fully protected Leu-enkephalin were measured to be identical in acetone solution. This allows the conclusion that neither of these peptide oxygens is hydrogen bonded and that no specific 2 ← 5 β-turn structure exists to an appreciable extent.

【 授权许可】

Unknown