期刊论文详细信息
FEBS Letters | |
Effects of benzyl alcohol on transferrin and low density lipoprotein receptor mediated endocytosis in leukemic guinea pig B lymphocytes | |
Vidal, M.1  Sainte-Marie, J.1  Bienvenüe, A.1  Vignes, M.1  Philippot, J.R.1  | |
[1] URA-CNRS 530, Interactions Membranaires, Dept. Biologie Santé USTL, 34095 Montpellier, France | |
关键词: Receptor endocytosis; Inhibition; Benzyl alcohol; L2C cell; | |
DOI : 10.1016/0014-5793(90)80141-5 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
We demonstrated that benzyl alcohol, a neutral local anesthetic drug, inhibits the uptake and degradation of lowdensity lipoprotein and endocytosis of transferrin receptors of guinea pig leukemic B lymphocytes (L2C). This inhibition is very rapid, concentration dependant and reversible by simple washing. Membrane fluidity of the living cells is also modified.
【 授权许可】
Unknown
【 预 览 】
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