Characterization of a cytotoxin‐like basic protein from the cobra (Naja naja naja) venom

FEBS Letters

Shafqat, Jawed¹  Zaidi, Zafar H.¹  Jörnvall, Hans² 

[1]HEJ Research Institute of Chemistry, University of Karachi, Karachi-32, Pakistan

[2]Department of Chemistry I, Karolinska Institutet, S-104 01 Stockholm, Sweden

关键词: Cytotoxin-like basic polypeptide;    Cobra venom;    Amino acid sequence;    Structure-function relationship;    Homology;   

DOI  :  10.1016/0014-5793(90)80563-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

A cytotoxin-like basic protein has been isolated from the venom of the nominate race of cobra (Naja naja naja from Pakistan) by a single step of high-performance liquid chromatography. The primary structure was determined and consists of 62 amino acid residues in a single polypeptide chain. It is highly similar to that of the cytotoxin-like basic proteins isolated from other Naja species, but differs in two of the SS-loop structures from that of cytotoxins.

【 授权许可】

Unknown