Metallothionein genes from the flowering plant Mimulus guttatus

FEBS Letters

Tomsett, A.B.¹  Thurman, D.A.¹  Thomas, M.A.¹  de Miranda, J.R.¹ 

[1] Department of Genetics and Microbiology, University of Liverpool, Liverpool L69 3BX, England

关键词: Class I metallothionein;    Plant metallothionein;    Metallothionein gene;    Root-specific;    Metal tolerance;    Metal metabolism;    MT;    metallothionein;    [γEC]n G;    poly(γ-glutamylcysteinyl) glycine or class III metallothionein;    γECG;    glutathione;   

DOI  :  10.1016/0014-5793(90)80122-Y

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

In response to excess metal, higher plants produce metal-binding peptides ([γEC]_nG) whose biosynthesis is believed to be mediated by enzymes involved in glutathione (γECG) metabolism. In contrast, animals synthesize metallothioneins, gene-encoded low molecular weight cysteine-rich metal-binding proteins. In an investigation of copper-regulated genes in the copper-tolerant flowering plant Mimulus guttatus, we have isolated a series of cDNA clones identifying two genes which encode a protein with class I metallothionein domains. This represents the first description of a metallothionein gene in a flowering plant.

【 授权许可】

Unknown