Pulse radiolysis study on the reactivity of Trolox C phenoxyl radical with superoxide anion

FEBS Letters

Merényi, Gabor³  Lind, Johan¹  Cadenas, Enrique² 

[1] Department of Nuclear Chemistry, Royal Institute of Technology, S-100 44 Stockholm, Sweden;Department of Pathology II, University of Linköping, S-581 85 Linköping, Sweden;Department of Physical Chemistry, Royal Institute of Technology, S-100 44 Stockholm Sweden

关键词: Superoxide radical;    Trolox C;    Vitamin E;    Phenoxyl radical;    Pulse radiolysis;    T-OH;    Trolox C (6-hydroxy-2;    5;    7;    8-tetramethylchroman-2-carboxylic acid);    α-T-OH;    α-tocopherol;   

DOI  :  10.1016/0014-5793(89)80966-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The reaction between the phenoxyl radical of Trolox C, a water-soluble vitamin E analogue, and superoxide anion radical was examined by using the pulse radiolysis technique. The results indicate that the Trolox C phenoxyl radical may undergo a rapid one-electron transfer from superoxide radical [k=(4.5±0.5) × 10⁸ M⁻¹·s⁻¹] to its reduced form. This finding indicates that superoxide radical might play a role in the repair of vitamin E phenoxyl radical.

【 授权许可】

Unknown