Remarks on the supramolecular organization of the glycolytic system in vivo

FEBS Letters

Batke, J.¹ 

[1] Institute of Enzymology, Biological Research Center, Hungarian Academy of Sciences, PO Box 7, Budapest H-1502, Hungary

关键词: Supramolecular organization;    Glycolytic system;    Ald or aldolase;    fructose-1;    6-bisphosphate aldolase;    CaM;    calmodulin;    FBP-ase;    fructose-1;    6-bisphosphatase;    GAPD;    glyceraldehyde-3-phosphate dehydrogenase;    GDH;    glycerolphosphate dehydrogenase;    LDH;    lactate dehydrogenase;    PFK;    phosphofructokinase;    PGK;    phosphoglycerate kinase;    PK;    pyruvate kinase;    TPI;    triosephosphate isomerase;   

DOI  :  10.1016/0014-5793(89)81419-X

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The great latent catalytic capacity, manifested at the extremely high intracellular concentrations and in large apparent k _cat/K _m values, of the glycolytic enzymes on the one hand and their tendency in experiments in vitro to form functionally-specific flux-enhancing (channeling) complexes on the other, is considered and discussed as an apparent discrepancy. A random association of glycolytic enzymes in vivo is probable.

【 授权许可】

Unknown