Hydrogen peroxide is the end product of oxygen reduction by the terminal oxidase in the marine bacterium Pseudomonas nautica 617

FEBS Letters

Arnaud, Sylvain¹  Malatesta, Francesco²  Denis, Michel¹ 

[1] Centre d'Océanologie de Marseille, CNRS UA 41, Faculté des Sciences de Luminy, Case 901, 13288 Marseille Cedex 9, France;Deparment of Experimental Medicine and Biochemical Sciences, University of Rome ‘Tor Vergata’, Piazzale Aldo Moro 5, 00185 Rome, Italy

关键词: Bacterial oxidase;    Oxygen reduction;    Hydrogen peroxide;    (Pseudomonas nautica 617);   

DOI  :  10.1016/0014-5793(89)81394-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Mitochondrial cytochrome-c oxidase as well as several bacterial oxidases are known to reduce dioxygen to water. For the first time, a heme-containing oxidase, the terminal enzyme of the aerobic respiratory system in the marine bacterium Pseudomonas nautica 617, is shown to reduce molecular oxygen only to hydrogen peroxide. Whereas the cell content is well protected from H₂O₂, by catalase, the possible efflux of H₂O₂, into seawater could play an important role in the environment.

【 授权许可】

Unknown