Coupling of viral membrane proteins to phosphatidylinositide signalling system

FEBS Letters

Koschel, Klaus¹  Weinmann-Dorsch, Christa¹ 

[1] Institut für Virologie und Immunbiologie der Universität Würzburg, Versbacher Str. 7, D-8700 Würzburg, FRG

关键词: Persistent virus infection;    Antimeasles antibody;    Phosphinositide turnover;    (Glioma cell);    PtdInsP2;    phosphatidylinositol 4;    5-bisphosphate;    PtdInsP;    phosphatidylinositol 4-phosphate;    InsP3;    inositol 1;    4;    5-trisphosphate;    InsP2;    inositol 1;    4-bisphosphate;    InsP1;    inositol 1-monophosphate;    HA;    haemagglutinin;    SSPE;    subacute sclerosing panencephalitis;    IgGm;    purified antimeasles IgG;    FCS;    fetal calf serum;   

DOI  :  10.1016/0014-5793(89)81330-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

C6 rat glioma cells persistently infected with subacute sclerosing panencephalitis virus (C6/SSPE) were treated with measles antiserum and purified anti-measles IgG. This stimulated phosphoinositide breakdown and an increase in inositol phosphates. In uninfected C6 cells, however, only fetal calf serum (FCS), but not measles anti serum could induce inositol polyphosphate production.

【 授权许可】

Unknown