Prothymosin α is a nuclear protein

FEBS Letters

Cary, Peter D.¹  Crane-Robinson, Colyn¹  Watts, Julian D.¹ 

[1] Biophysics Laboratories, Portsmouth Polytechnic, White Swan Road, Portsmouth PO1 2DT, England

关键词: Prothymosin α;    Thymosin;    Nuclear targeting;   

DOI  :  10.1016/0014-5793(89)80182-6

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

The cellular location of the so-called ‘thymic hormone’ prothymosin α has been studied by microinjection into the cytoplasm of Xenopus oocytes, followed by separate monitoring of nuclear and cytoplasmic concentrations. It is shown that prothymosin α migrates to the nucleus at a rate comparable to that of histone H1. Prothymosin α cannot therefore be a hormone in the usual sense of the word.

【 授权许可】

Unknown