期刊论文详细信息
FEBS Letters | |
Protein kinase C is involved in regulation of Ca2+ channels in plasmalemma of Nitella syncarpa | |
Zherelova, O.M.1  | |
[1] Institute of Biological Physics, Acad. Sci. USSR, Pushchino, Moscow Region 142292, USSR | |
关键词: C2+ channel; Protein kinase C; (Nitella syncarpa); | |
DOI : 10.1016/0014-5793(89)80495-8 | |
学科分类:生物化学/生物物理 | |
来源: John Wiley & Sons Ltd. | |
【 摘 要 】
Ca2+ current recordings have been made on Nitella syncarpa cells using the intracellular perfusion and the voltage-clamp technique. TPA (12-O-tetradecanoylphorbol-13-acetate), a substance capable of activating protein kinase C from plasmalemma of Nitella cells, modulates voltage-dependent Ca2+ channels. Polymixin B, inhibitor of protein kinase C, blocks the Nitella plasmalemma Ca2+ channels; the rate of channel blockage depends on the concentration and exposure time of the substance.
【 授权许可】
Unknown
【 预 览 】
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