Protein kinase C is involved in regulation of Ca2+ channels in plasmalemma of Nitella syncarpa

FEBS Letters

Zherelova, O.M.¹ 

[1] Institute of Biological Physics, Acad. Sci. USSR, Pushchino, Moscow Region 142292, USSR

关键词: C2+ channel;    Protein kinase C;    (Nitella syncarpa);   

DOI  :  10.1016/0014-5793(89)80495-8

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Ca²⁺ current recordings have been made on Nitella syncarpa cells using the intracellular perfusion and the voltage-clamp technique. TPA (12-O-tetradecanoylphorbol-13-acetate), a substance capable of activating protein kinase C from plasmalemma of Nitella cells, modulates voltage-dependent Ca²⁺ channels. Polymixin B, inhibitor of protein kinase C, blocks the Nitella plasmalemma Ca²⁺ channels; the rate of channel blockage depends on the concentration and exposure time of the substance.

【 授权许可】

Unknown