An endogenous ligand for the central sulfonylurea receptor

FEBS Letters

Bataille, D.¹  Brück, M.¹  Lupo, B.¹  Dufour, M.¹  Cauvin, A.²  Virsolvy-Vergine, A.¹ 

[1] Centre CNRS-INSERM de Pharmacologie-Endocrinologie, Rue de la Cardonille, 34094 Montpellier Cedex 2, France;Laboratoire de Chimie Biologique et de la Nutrition, Bd de Waterloo 115, B-1000 Bruxelles, Belgium

关键词: Hypoglycemic sulfonylurea;    Central receptor;    Endogenous ligand;    Peptide;   

DOI  :  10.1016/0014-5793(88)80986-4

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

An endogenous ligand for the rat central sulfonylurea receptor has been evidenced in the rat central nervous system. The characteristics of this ligand (extractibility, non-dialysability, chromatographic behaviour on different media, sensitivity to proteases) indicate that it is a neutral to slightly basic peptide.

【 授权许可】

Unknown