The reactivation of apodopamine β‐monooxygenase by vanadyl ions

FEBS Letters

Nalbandyan, R.M.¹  Paitian, N.A.¹  Markossian, K.A.¹ 

[1] Institute of Biochemistry, Academy of Sciences, Armenian SSR, Yerevan 375044, USSR

关键词: Dopamine β-monooxygenase;    Vanadyl ion;    Copper ion;   

DOI  :  10.1016/0014-5793(88)80520-9

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Vanadyl ions may be used for reactivation of apodopamine β-monooxygenase. Maximal activity of the enzyme was achieved at a 350–400-fold molar excess of vanadyl ions, whereas for maximal reconstitution with copper, an 8–10-fold molar excess of copper was necessary. At higher concentrations of vanadyl as well as of copper, inhibition was observed.

【 授权许可】

Unknown