Bioenergetics of dihydrostreptomycin transport by Escherichia coli

FEBS Letters

Spicer, Alan B.¹  Goss, Stephen R.²  Nichols, Wright W.² 

[1] Department of Biology, Oxford Polytechnic, Oxford OX3 0BP, England;Public Health Laboratory, Level 6/7, John Radcliffe Hospital, Oxford OX3 9DU England

关键词: Dihydrostreptomycin transport;    Streptomycin uptake;    Transport kinetics;    Membrane potential;    (Escherichia coli);   

DOI  :  10.1016/0014-5793(88)80008-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Previous demonstrations of the irreversibility of dihydrostreptomycin transport across the cytoplasmic membrane of Escherichia coli were not due to decreases in the magnitude of the cytoplasmic membrane potential (Δψ). Irreversibility was probably not due to ATP hydrolysis being coupled to transport, because the rate of energy-dependent dihydrostreptomycin uptake was unaffected by 10-fold reduction in the cellular ATP level.

【 授权许可】

Unknown