Hormone (pheromone) processing enzymes in yeast The carboxy‐terminal processing enzyme of the mating pheromone α‐factor, carboxypeptidase yscα, is absent in α‐factor maturation‐defective kex1 mutant cells

FEBS Letters

Wagner, Jean-Claude¹  Wolf, Dieter H.¹ 

[1] Biochemisches Institut der Universität Freiburg i.Breisgau, Hermann-Herder-Straße 7, D-7800 Freiburg, FRG

关键词: Sex pheromone;    Protein precursor;    Hormone processing;    Carboxypeptidase yscα;    (Yeast mutant;    Saccharomyces cerevisiae);   

DOI  :  10.1016/0014-5793(87)80967-5

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

Carboxy-terminal processing of the mating pheromone α-factor of the yeast Saccharomyces cerevisiae has been assumed to be due to the action of carboxypeptidase yscα. [(1985) EMBO J. 4, 173–177]. Here it is shown that a mutant (kex1) defective in α-factor maturation is defective in carboxypeptidase yscα activity, indicating that the enzyme is indeed the processing catalyst. It is proposed that carboxypeptidase yscα is the product of the KEX1 gene.

【 授权许可】

Unknown