Retinal photoreceptor neurons and pinealocytes accumulate mRNA for interphotoreceptor retinoid‐binding protein (IRBP)

FEBS Letters

Chader, Gerald J.²  Katial, Albine¹  Nickerson, John M.²  Wiggert, B.²  van Veen, Theo²  Barrett, D.J.²  Shinohara, Toshimichi³ 

[1] Digene, College Park, MD, USA;Zoology Department, University of Lund, Lund, Sweden;Laboratory of Molecular and Developmental Biology, MD and Laboratory of Retinal Cell and Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA

关键词: Interphotoreceptor retinoid-binding protein cDNA Hybridization Rod photoreceptor cell Pinealocyte;   

DOI  :  10.1016/0014-5793(86)81547-2

学科分类：生物化学/生物物理

来源: John Wiley & Sons Ltd.

【 摘 要 】

We have utilized cDNA probes and in situ hybridization techniques to define the subcellular localization of interphotoreceptor retinoid-binding protein (IRBP) mRNA in bovine and monkey retinas. Results suggest that the mRNA is mainly localized in rod photoreceptor neurons within the outer nuclear layer of the retina. IRBP mRNA is also abundant in cells of the pineal gland, strengthening the analogy between rod photoreceptor cells and pinealocytes.

【 授权许可】

Unknown